PKRRATING - AN OVERVIEW

3B). R526 within the loop involving αJ and αI anchors the C-terminal percentage of the activation loop by forming a salt bridge with E458 at The bottom of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the most crucial chain carbonyl of R413. The tip of your activation phase is stabilized by a hydrogen bond in between Y454 and E480 fro